Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target

Cytochrome P450-mediated metabolism of arachidonic acid (AA) is an important pathway for the formation of eicosanoids. The ω-hydroxylation of AA generates significant levels of 20-hydroxyeicosatetraenoic acid (20-HETE) in various tissues. In the current review, we discussed the role of 20-HETE in th...

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Bibliographic Details
Main Authors: Osama H. Elshenawy, Sherif M. Shoieb, Anwar Mohamed, Ayman O.S. El-Kadi
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/9/1/9