TP53 mutation spectrum in smokers and never smoking lung cancer patients

TP53 mutation spectrum in smokers and never smoking lung cancer patients

AbstractBackground: TP53 mutations are among the most common mutations found in lung cancers, identified as an independent prognostic factor in many types of cancers. The purpose of this study was to investigate the frequency and prognostic impact of TP53 mutations in never-smokers and in different...

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Bibliographic Details
Main Authors: Ann Rita Halvorsen, Laxmi eSilwal-Pandit, Leonardo A Meza-Zepeda, Daniel eVodak, Phuong eVu, Camilla eSagerup, Eivind eHovig, Ola eMyklbost, Anne-Lise eBørresen-Dale, Odd Terje Brustugun, Åslaug eHelland
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Genetics
Subjects:
lung cancer
TP53
Mutation spectrum
Squamous cell carcinomas
Never smokers
Adenocarcinomas
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00085/full

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http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00085/full

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