The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

<p>Abstract</p> <p>Background</p> <p>TMEM18 is a hypothalamic gene that has recently been linked to obesity and BMI in genome wide association studies. However, the functional properties of TMEM18 are obscure.</p> <p>Methods</p> <p>The evolutiona...

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Bibliographic Details
Main Authors: Levine Allen S, Sreedharan Smitha, Alsiö Johan, Cedernaes Jonathan, Olszewski Pawel K, Shaik Jafar HA, Jacobsson Josefin A, Almén Markus, Fredriksson Robert, Marcus Claude, Schiöth Helgi B
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/11/58