Role of ErbB receptors in cancer cell migration and invasion

Growth factors mediate their diverse biologic responses (regulation of cellular proliferation, differentiation, migration and survival) by binding to and activating cell-surface receptors with intrinsic protein kinase activity named Receptor Tyrosine Kinases (RTKs). About 60 RTKs have been identifie...

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Bibliographic Details
Main Authors: Aline eAppert-Collin, Pierre eHubert, Gerard eCremel, Amar eBennasroune
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00283/full