Fragmentation of SIV-gag vaccine induces broader T cell responses.

Fragmentation of SIV-gag vaccine induces broader T cell responses.

High mutation rates of human immunodeficiency virus (HIV) allows escape from T cell recognition preventing development of effective T cell vaccines. Vaccines that induce diverse T cell immune responses would help overcome this problem. Using SIV gag as a model vaccine, we investigated two approaches...

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Bibliographic Details
Main Authors: Adel Benlahrech, Andrea Meiser, Shanthi Herath, Timos Papagatsias, Takis Athanasopoulos, Fucheng Li, Steve Self, Veronique Bachy, Catherine Hervouet, Karen Logan, Linda Klavinskis, George Dickson, Steven Patterson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485275?pdf=render

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http://europepmc.org/articles/PMC3485275?pdf=render

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