Urothelium proliferation is a trigger for renal crystal deposits in a murine lithogenesis model

Urothelium proliferation is a trigger for renal crystal deposits in a murine lithogenesis model

Abstract Most mouse kidney stone models induce nephrocalcinosis rather than urolithiasis. The aim of our study was to find an accelerated experimental model in order to study the early events of stone formation, that is, at the time of crystal binding to intrarenal urothelium. C57B6 mice exposed to...

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Bibliographic Details
Main Authors: Héloïse Bilbault, Joëlle Perez, Léa Huguet, Sophie Vandermeersch, Sandrine Placier, Nahid Tabibzadeh, Vincent Frochot, Emmanuel Letavernier, Dominique Bazin, Michel Daudon, Jean-Philippe Haymann
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Scientific Reports
Subjects:
Urothelial Cell Proliferation
Crystal Deposition
FGF7 Groups
FGF7 Administration
Crystal Retention
Online Access:https://doi.org/10.1038/s41598-018-34734-8

Internet

https://doi.org/10.1038/s41598-018-34734-8

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