Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids

Abstract Background Restoration of endothelial glycocalyx (EG) barrier may be an essential therapeutic target for successful resuscitation. The aim of this study was to compare in vivo the effects of resuscitation with normal saline (NS) to lactated Ringer’s solution (LR), 5% albumin and fresh froze...

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Bibliographic Details
Main Authors: Luciana N. Torres, Kevin K. Chung, Christi L. Salgado, Michael A. Dubick, Ivo P. Torres Filho
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Critical Care
Subjects:
Critical care
Microcirculation
Permissive hypotension
Leukocyte
Barrier function
Permeability
Online Access:http://link.springer.com/article/10.1186/s13054-017-1745-7

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http://link.springer.com/article/10.1186/s13054-017-1745-7

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