Additional germline findings from a tumor profiling program

Additional germline findings from a tumor profiling program

Abstract Background Matched tumor-normal sequencing, applied in precision cancer medicine, can identify unidentified germline Medically Actionable Variants (gMAVS) in cancer predisposition genes. We report patient preferences for the return of additional germline results, and describe various gMAV s...

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Bibliographic Details
Main Authors: Neda Stjepanovic, Tracy L. Stockley, Philippe L. Bedard, Jeanna M. McCuaig, Melyssa Aronson, Spring Holter, Kara Semotiuk, Natasha B. Leighl, Raymond Jang, Monika K. Krzyzanowska, Amit M. Oza, Abha Gupta, Christine Elser, Lailah Ahmed, Lisa Wang, Suzanne Kamel-Reid, Lillian L. Siu, Raymond H. Kim
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Medical Genomics
Subjects:
Germline mutation
Neoplasms/genetics
Neoplastic syndromes
Hereditary Cancer
Incidental findings
Secondary findings
Online Access:http://link.springer.com/article/10.1186/s12920-018-0383-5

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http://link.springer.com/article/10.1186/s12920-018-0383-5

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