LPS immune challenge reduces arcuate nucleus TSHR and CART mRNA and elevates plasma CART peptides

Abstract Background The aim was to examine the impact of lipopolysaccharide-induced systemic inflammation on expression of mRNA for cocaine- and amphetamine-regulated transcript (CART) and the thyrotropin receptor (TSHR) and its ligands in CNS areas of relevance for feeding controls and metabolism....

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Bibliographic Details
Main Authors: Jonathan R. Burgos, Britt-Marie Iresjö, Linda Olsson, Ulrika Smedh
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-019-0539-z