Targeted and reversible cancer cell-binding DNA nanoparticles
DNA nanoparticles (DeNAno) produced by rolling circle replication of circular oligonucleotide templates are a novel format for the selection of cell-binding reagents from randomized libraries. DeNAno particles consist of several hundred concatemers and can leverage that multivalency to bind to compl...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2014-12-01
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Series: | Nanotechnology Reviews |
Subjects: | |
Online Access: | https://doi.org/10.1515/ntrev-2014-0010 |