Targeted and reversible cancer cell-binding DNA nanoparticles

DNA nanoparticles (DeNAno) produced by rolling circle replication of circular oligonucleotide templates are a novel format for the selection of cell-binding reagents from randomized libraries. DeNAno particles consist of several hundred concatemers and can leverage that multivalency to bind to compl...

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Bibliographic Details
Main Authors: Ruff Laura E., Marciniak Jennifer Y., Sanchez Ana B., Esener Sadik C., Messmer Bradley T.
Format: Article
Language:English
Published: De Gruyter 2014-12-01
Series:Nanotechnology Reviews
Subjects:
dna
Online Access:https://doi.org/10.1515/ntrev-2014-0010