Genetic Modification of Donor Hepatocytes Improves Therapeutic Efficacy for Hemophilia B in Mice

Hepatocyte transplantation (Tx) holds promise for curing genetic liver diseases. However, a limited number of donor hepatocytes can be transplanted into the host liver. Recipient preconditioning and donor cell engineering are under investigation to improve cell engraftment. In theory, genetically en...

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Bibliographic Details
Main Authors: Yao-Ming Wu, Chung-Yang Kao, Yu-Jen Huang, I-Shing Yu, Hsuan-Shu Lee, Hong-Shiee Lai, Po-Huang Lee, Chia-Ni Lin, Shu-Wha Lin
Format: Article
Language:English
Published: SAGE Publishing 2010-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X503398