Genetic Modification of Donor Hepatocytes Improves Therapeutic Efficacy for Hemophilia B in Mice
Hepatocyte transplantation (Tx) holds promise for curing genetic liver diseases. However, a limited number of donor hepatocytes can be transplanted into the host liver. Recipient preconditioning and donor cell engineering are under investigation to improve cell engraftment. In theory, genetically en...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-09-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368910X503398 |