Investigation of thromboxane A2 synthase knockout mice

by I-Shing Yu, 游益興
Published 2005

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy.

by Chen-Hsueh Pai, Ching-Tzu Yen, Chie-Pein Chen, I-Shing Yu, Shu-Wha Lin, Shu-Rung Lin
Published 2016-01-01

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells.

by Chun-Yu Chen, I-Shing Yu, Chen-Hsueh Pai, Chien-Yu Lin, Shu-Rung Lin, You-Tzung Chen, Shu-Wha Lin
Published 2019-01-01

Mice Lacking Connective Tissue Growth Factor in the Forebrain Exhibit Delayed Seizure Response, Reduced C-Fos Expression and Different Microglial Phenotype Following Acute PTZ Inje...

by Pei-Fen Siow, Chih-Yu Tsao, Ho-Ching Chang, Chwen-Yu Chen, I-Shing Yu, Kuang-Yung Lee, Li-Jen Lee
Published 2020-07-01

Sun1 deficiency leads to cerebellar ataxia in mice

by Jing-Ya Wang, I.-Shing Yu, Chien-Chi Huang, Chia-Yen Chen, Wan-Ping Wang, Shu-Wha Lin, Kuan-Teh Jeang, Ya-Hui Chi
Published 2015-08-01

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice.

by Ya-Yun Wang, Chih-Chun Ke, Yen-Lin Chen, Yu-Hua Lin, I-Shing Yu, Wei-Chi Ku, Moira K O'Bryan, Ying-Hung Lin
Published 2020-09-01

Genetic Modification of Donor Hepatocytes Improves Therapeutic Efficacy for Hemophilia B in Mice

by Yao-Ming Wu, Chung-Yang Kao, Yu-Jen Huang, I-Shing Yu, Hsuan-Shu Lee, Hong-Shiee Lai, Po-Huang Lee, Chia-Ni Lin, Shu-Wha Lin
Published 2010-09-01

SEPT12-Microtubule Complexes Are Required for Sperm Head and Tail Formation

by Yen-Ni Teng, Ying-Hung Lin, Shu-Wha Lin, I-Shing Yu, Mei-Feng Chen, Pao-Lin Kuo, Yung-Che Kuo, Ya-Yun Wang, Han-Sun Chiang
Published 2013-11-01

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

by Brian D. Adair, José L. Alonso, Johannes van Agthoven, Vincent Hayes, Hyun Sook Ahn, I-Shing Yu, Shu-Wha Lin, Jian-Ping Xiong, Mortimer Poncz, M. Amin Arnaout
Published 2020-01-01

Differences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and mice.

by Ying-Chang Lu, Chen-Chi Wu, Ting-Hua Yang, Yin-Hung Lin, I-Shing Yu, Shu-Wha Lin, Qing Chang, Xi Lin, Jau-Min Wong, Chuan-Jen Hsu
Published 2014-01-01

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation

by Chih-Yuan Lee, Ting-Yu Lai, Meng-Kun Tsai, Yung-Chi Chang, Yu-Hsin Ho, I-Shing Yu, Tzu-Wen Yeh, Chih-Chang Chou, You-Sheng Lin, Toby Lawrence, Li-Chung Hsu
Published 2017-06-01

Aryl hydrocarbon receptor downregulates MYCN expression and promotes cell differentiation of neuroblastoma.

by Pei-Yi Wu, Yung-Feng Liao, Hsueh-Fen Juan, Hsuan-Cheng Huang, Bo-Jeng Wang, Yen-Lin Lu, I-Shing Yu, Yu-Yin Shih, Yung-Ming Jeng, Wen-Ming Hsu, Hsinyu Lee
Published 2014-01-01

Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

by Chen-Hsueh Pai, Shu-Rung Lin, Chia-Hao Liu, Szu-Yu Pan, Hao Hsu, Yi-Ting Chen, Ching-Tzu Yen, I-Shing Yu, Hua-Lin Wu, Shuei-Liong Lin, Shu-Wha Lin
Published 2020-10-01

Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency

by Ni-Chung Lee, Yih-Dar Shieh, Yin-Hsiu Chien, Kai-Yuan Tzen, I-Shing Yu, Pin-Wen Chen, Min-Hsiu Hu, Meng-kai Hu, Shin-ichi Muramatsu, Hiroshi Ichinose, Wuh-Liang Hwu
Published 2013-04-01

Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation

by Chia-Ching Lin, Yi-Ru Shen, Chi-Chih Chang, Xiang-Yi Guo, Yun-Yun Young, Ting-Yu Lai, I-Shing Yu, Chih-Yuan Lee, Tsung-Hsien Chuang, Hsin-Yue Tsai, Li-Chung Hsu
Published 2021-06-01

Genetic Elimination of Connective Tissue Growth Factor in the Forebrain Affects Subplate Neurons in the Cortex and Oligodendrocytes in the Underlying White Matter

by I-Shing Yu, Ho-Ching Chang, Ko-Chien Chen, Yi-Ling Lu, Horng-Tzer Shy, Chwen-Yu Chen, Kuang-Yung Lee, Kuang-Yung Lee, Li-Jen Lee, Li-Jen Lee, Li-Jen Lee
Published 2019-02-01

Toward the Pathogenicity of the<i> SLC26A4 </i>p.C565Y Variant Using a Genetically Driven Mouse Model

by Chin-Ju Hu, Ying-Chang Lu, Ting-Hua Yang, Yen-Hui Chan, Cheng-Yu Tsai, I-Shing Yu, Shu-Wha Lin, Tien-Chen Liu, Yen-Fu Cheng, Chen-Chi Wu, Chuan-Jen Hsu
Published 2021-03-01

Establishment of a knock-in mouse model with the SLC26A4 c.919-2A>G mutation and characterization of its pathology.

by Ying-Chang Lu, Chen-Chi Wu, Wen-Sheng Shen, Ting-Hua Yang, Te-Huei Yeh, Pei-Jer Chen, I-Shing Yu, Shu-Wha Lin, Jau-Min Wong, Qing Chang, Xi Lin, Chuan-Jen Hsu
Published 2011-01-01

A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.

by Jin-Bon Hong, Fu-Ju Chou, Amy T Ku, Hsiang-Hsuan Fan, Tung-Lung Lee, Yung-Hsin Huang, Tsung-Lin Yang, I-Chang Su, I-Shing Yu, Shu-Wha Lin, Chung-Liang Chien, Hong-Nerng Ho, You-Tzung Chen
Published 2014-01-01

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

by Sunglim Cho, Hyang-Mi Lee, I-Shing Yu, Youn Soo Choi, Hsi-Yuan Huang, Somaye Sadat Hashemifar, Ling-Li Lin, Mei-Chi Chen, Nikita D. Afanasiev, Aly Azeem Khan, Shu-Wha Lin, Alexander Y. Rudensky, Shane Crotty, Li-Fan Lu
Published 2018-07-01