Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

by Grégory Verdeil, Toby Lawrence, Anne-Marie Schmitt-Verhulst, Nathalie Auphan-Anezin
Published 2019-11-01

PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses

by Hannah Wilkinson, Hugh Leonard, Daxin Chen, Toby Lawrence, Michael Robson, Pieter. Goossens, John H. McVey, Anthony Dorling
Published 2021-01-01

The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity.

by Magali Bebien, Mary E Hensler, Suzel Davanture, Li-Chung Hsu, Michael Karin, Jin Mo Park, Lena Alexopoulou, George Y Liu, Victor Nizet, Toby Lawrence
Published 2012-01-01

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

by Mohamed Habbeddine, Christophe Verthuy, Olivia Rastoin, Lionel Chasson, Magali Bebien, Marc Bajenoff, Sahil Adriouch, Joke M.M. den Haan, Josef M. Penninger, Toby Lawrence
Published 2017-11-01

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation

by Chih-Yuan Lee, Ting-Yu Lai, Meng-Kun Tsai, Yung-Chi Chang, Yu-Hsin Ho, I-Shing Yu, Tzu-Wen Yeh, Chih-Chang Chou, You-Sheng Lin, Toby Lawrence, Li-Chung Hsu
Published 2017-06-01

Correction: Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

by Joseph M. D. Rastrick, Christopher S. Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M. Evans, Manolis Pasparakis, Matthew C. Catley, Toby Lawrence, Ian M. Adcock, Maria G. Belvisi, Mark A. Birrell
Published 2013-01-01

Correction: Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling.

by Joseph M. D. Rastrick, Christopher S. Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M. Evans, Manolis Pasparakis, Matthew C. Catley, Toby Lawrence, Ian M. Adcock, Maria G. Belvisi, Mark A. Birrell
Published 2013-01-01

Cigarette smoke induced airway inflammation is independent of NF-κB signalling.

by Joseph M D Rastrick, Christopher S Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M Evans, Manolis Pasparakis, Matthew C Catley, Toby Lawrence, Ian M Adcock, Maria G Belvisi, Mark A Birrell
Published 2013-01-01

Tracking Dynamics of Spontaneous Tumors in Mice Using Photon-Counting Computed Tomography

by Franca Cassol, Loriane Portal, Sylvie Richelme, Mathieu Dupont, Yannick Boursier, Maria Arechederra, Nathalie Auphan-Anezin, Lionel Chasson, Caroline Laprie, Samantha Fernandez, Laure Balasse, Fabienne Lamballe, Rosanna Dono, Benjamin Guillet, Toby Lawrence, Christian Morel, Flavio Maina
Published 2019-11-01

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis

by Rong Huang, Guo Guo, Liaoxun Lu, Rui Fu, Jing Luo, Zhuangzhuang Liu, Yanrong Gu, Wenyi Yang, Qianqian Zheng, Tianzhu Chao, Le He, Ying Wang, Zhiguo Niu, Hui Wang, Toby Lawrence, Marie Malissen, Bernard Malissen, Yinming Liang, Lichen Zhang
Published 2019-12-01

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.

by Pathricia V Tilstam, Marion J Gijbels, Mohamed Habbeddine, Céline Cudejko, Yaw Asare, Wendy Theelen, Baixue Zhou, Yvonne Döring, Maik Drechsler, Lukas Pawig, Sakine Simsekyilmaz, Rory R Koenen, Menno P J de Winther, Toby Lawrence, Jürgen Bernhagen, Alma Zernecke, Christian Weber, Heidi Noels
Published 2014-01-01

Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice

by Tianzhu Chao, Tianzhu Chao, Zhuangzhuang Liu, Zhuangzhuang Liu, Yu Zhang, Yu Zhang, Lichen Zhang, Lichen Zhang, Rong Huang, Rong Huang, Le He, Le He, Yanrong Gu, Yanrong Gu, Zhijun Chen, Zhijun Chen, Qianqian Zheng, Qianqian Zheng, Lijin Shi, Lijin Shi, Wenping Zheng, Wenping Zheng, Xinhui Qi, Xinhui Qi, Eryan Kong, Zhongjian Zhang, Toby Lawrence, Yinming Liang, Yinming Liang, Yinming Liang, Liaoxun Lu, Liaoxun Lu, Liaoxun Lu
Published 2019-02-01