Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation.

Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation.

Product of the Itga2b gene, CD41 contributes to hematopoietic stem cell (HSC) and megakaryocyte/platelet functions. CD41 expression marks the onset of definitive hematopoiesis in the embryo where it participates in regulating the numbers of multipotential progenitors. Key to platelet aggregation, CD...

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Bibliographic Details
Main Authors: Stephanie Dumon, David S Walton, Giacomo Volpe, Nicola Wilson, Emilie Dassé, Walter Del Pozzo, Josette-Renee Landry, Bryan Turner, Laura P O'Neill, Berthold Göttgens, Jon Frampton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429474?pdf=render

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http://europepmc.org/articles/PMC3429474?pdf=render

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