Effect of NAD+ boosting on kidney ischemia-reperfusion injury.

Acute kidney injury (AKI) is associated with a very high mortality and an increased risk for progression to chronic kidney disease (CKD). Ischemia-reperfusion injury (IRI) is a model for AKI, which results in tubular damage, dysfunction of the mitochondria and autophagy, and in decreased cellular ni...

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Bibliographic Details
Main Authors: Marya Morevati, Søren Egstrand, Anders Nordholm, Maria L Mace, Claus B Andersen, Rouzbeh Salmani, Klaus Olgaard, Ewa Lewin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0252554