Bacterial persisters are a stochastically formed subpopulation of low-energy cells.

Persisters represent a small subpopulation of non- or slow-growing bacterial cells that are tolerant to killing by antibiotics. Despite their prominent role in the recalcitrance of chronic infections to antibiotic therapy, the mechanism of their formation has remained elusive. We show that sorted ce...

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Bibliographic Details
Main Authors: Sylvie Manuse, Yue Shan, Silvia J Canas-Duarte, Somenath Bakshi, Wei-Sheng Sun, Hirotada Mori, Johan Paulsson, Kim Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001194