Identification of novel GNAS mutations in intramuscular myxoma using next-generation sequencing with single-molecule tagged molecular inversion probes

Identification of novel GNAS mutations in intramuscular myxoma using next-generation sequencing with single-molecule tagged molecular inversion probes

Abstract Background Intramuscular myxoma (IM) is a hypocellular benign soft tissue neoplasm characterized by abundant myxoid stroma and occasional hypercellular areas. These tumors can, especially on biopsy material, be difficult to distinguish from low-grade fibromyxoid sarcoma or low-grade myxofib...

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Bibliographic Details
Main Authors: Elise M. Bekers, Astrid Eijkelenboom, Paul Rombout, Peter van Zwam, Suzanne Mol, Emiel Ruijter, Blanca Scheijen, Uta Flucke
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Diagnostic Pathology
Subjects:
Next generation sequencing
TaqMan genotyping
smMIP assay
GNAS mutation
Intramuscular myxoma
Online Access:http://link.springer.com/article/10.1186/s13000-019-0787-3

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http://link.springer.com/article/10.1186/s13000-019-0787-3

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