Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes

Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes

Abstract Background Colorectal cancer (CRC) remains a leading cause of death worldwide. Utilizing cisplatin in CRC is correlated with severe adverse effects and drug-resistance. Combined anticancer drug-treatment, along with, their enhanced delivery, can effectively kill cancer through multiple path...

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Bibliographic Details
Main Authors: Mona M. Saber, Abdulaziz M. Al-mahallawi, Noha N. Nassar, Björn Stork, Samia A. Shouman
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
AMPK
Cisplatin
Metformin
mTOR
Nano-cubosomes
Online Access:http://link.springer.com/article/10.1186/s12885-018-4727-5

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http://link.springer.com/article/10.1186/s12885-018-4727-5

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