Hormonal regulation of cholesterol 7alpha-hydroxylase specific activity, mRNA levels, and transcriptional activity in vivo in the rat

In primary cultures of rat hepatocytes, transcription of the cholesterol 7alpha-hydroxylase gene is induced synergistically by glucocorticoid and thyroid hormones. The objective of the present study was to evaluate the role of endogenous glucocorticoid and thyroid hormones in the maintenance of chol...

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Bibliographic Details
Main Authors: W M Pandak, D M Heuman, K Redford, R T Stravitz, J Y Chiang, P B Hylemon, Z R Vlahcevic
Format: Article
Language:English
Published: Elsevier 1997-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752030033X