A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

Abstract In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated workflow were optimized to be adapted for probing m...

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Bibliographic Details
Main Authors: Julia Zwirchmayr, Benjamin Kirchweger, Theresa Lehner, Ammar Tahir, Dagmar Pretsch, Judith M. Rollinger
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-69186-6