Vagal control of the heart decreases during increasing imminence of interoceptive threat in patients with panic disorder and agoraphobia

Abstract Theoretically, panic disorder and agoraphobia pathology can be conceptualized as a cascade of dynamically changing defensive responses to threat cues from inside the body. Guided by this trans-diagnostic model we tested the interaction between defensive activation and vagal control as a mar...

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Bibliographic Details
Main Authors: Jan Richter, Anne Pietzner, Julian Koenig, Julian F. Thayer, Christiane A. Pané-Farré, Alexander L. Gerlach, Andrew T. Gloster, Hans-Ulrich Wittchen, Thomas Lang, Georg W. Alpers, Sylvia Helbig-Lang, Jürgen Deckert, Thomas Fydrich, Lydia Fehm, Andreas Ströhle, Tilo Kircher, Volker Arolt, Alfons O. Hamm
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86867-y