Cytotoxicity and Genotoxicity Evaluation of Organochalcogens in Human Leucocytes: A Comparative Study between Ebselen, Diphenyl Diselenide, and Diphenyl Ditelluride

Organochalcogens, particularly ebselen, have been used in experimental and clinical trials with borderline efficacy. (PhSe)2 and (PhTe)2 are the simplest of the diaryl dichalcogenides and share with ebselen pharmacological properties. In view of the concerns with the use of mammals in studies and th...

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Bibliographic Details
Main Authors: Diones Caeran Bueno, Daiane Francine Meinerz, Josiane Allebrandt, Emily Pansera Waczuk, Danúbia Bonfanti dos Santos, Douglas Oscar Ceolin Mariano, João Batista Teixeira Rocha
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/537279