A possible link between astrocyte activation and tau nitration in Alzheimer's disease

A possible link between astrocyte activation and tau nitration in Alzheimer's disease

Alzheimer's disease (AD) pathology has been characterized, in part, by the self-assembly of the tau molecule into neurofibrillary tangles (NFT). While different post-translational modifications have been identified that accelerate tau aggregation, nitration at tyrosine residues prevents or slow...

Full description

Bibliographic Details
Main Authors: Juan F. Reyes, Matthew R. Reynolds, Peleg M. Horowitz, Yifan Fu, Angela L. Guillozet-Bongaarts, Robert Berry, Lester I. Binder
Format: Article
Language:English
Published: Elsevier 2008-08-01
Series:Neurobiology of Disease
Subjects:
Tau
Nitration
Alzheimer's disease
Astrocytes
Monoclonal antibody
Glial fibrillary acidic protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000752

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108000752

Similar Items