A possible link between astrocyte activation and tau nitration in Alzheimer's disease

A possible link between astrocyte activation and tau nitration in Alzheimer's disease

Alzheimer's disease (AD) pathology has been characterized, in part, by the self-assembly of the tau molecule into neurofibrillary tangles (NFT). While different post-translational modifications have been identified that accelerate tau aggregation, nitration at tyrosine residues prevents or slow...

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Bibliographic Details
Main Authors:	Juan F. Reyes, Matthew R. Reynolds, Peleg M. Horowitz, Yifan Fu, Angela L. Guillozet-Bongaarts, Robert Berry, Lester I. Binder
Format:	Article
Language:	English
Published:	Elsevier 2008-08-01
Series:	Neurobiology of Disease
Subjects:	Tau Nitration Alzheimer's disease Astrocytes Monoclonal antibody Glial fibrillary acidic protein
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996108000752

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