Neoadjuvant chemoradiotherapy plus surgery versus active surveillance for oesophageal cancer: a stepped-wedge cluster randomised trial

Neoadjuvant chemoradiotherapy plus surgery versus active surveillance for oesophageal cancer: a stepped-wedge cluster randomised trial

Abstract Background Neoadjuvant chemoradiotherapy (nCRT) plus surgery is a standard treatment for locally advanced oesophageal cancer. With this treatment, 29% of patients have a pathologically complete response in the resection specimen. This provides the rationale for investigating an active surve...

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Bibliographic Details
Main Authors: Bo Jan Noordman, Bas P. L. Wijnhoven, Sjoerd M. Lagarde, Jurjen J. Boonstra, Peter Paul L. O. Coene, Jan Willem T. Dekker, Michael Doukas, Ate van der Gaast, Joos Heisterkamp, Ewout A. Kouwenhoven, Grard A. P. Nieuwenhuijzen, Jean-Pierre E. N. Pierie, Camiel Rosman, Johanna W. van Sandick, Maurice J. C. van der Sangen, Meindert N. Sosef, Manon C. W. Spaander, Roelf Valkema, Edwin S. van der Zaag, Ewout W. Steyerberg, J. Jan B. van Lanschot, on behalf of the SANO-study group
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
Oesophageal cancer
Neoadjuvant chemoradiotherapy
Active surveillance
Standard oesophagectomy
Online Access:http://link.springer.com/article/10.1186/s12885-018-4034-1

Internet

http://link.springer.com/article/10.1186/s12885-018-4034-1

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