The effect of tranilast on fibroblast activation protein α (FAP-α) expression in normal and keloid fibroblasts in vitro

The effect of tranilast on fibroblast activation protein α (FAP-α) expression in normal and keloid fibroblasts in vitro

Introduction . Tranilast (N-(3’,4’-demethoxycinnamoyl)-anthranilic acid) is an anti-allergic drug. Its mechanism of action is based on the inhibition of antigen-induced release of chemical mediators from mast cells and basophils. It also reveals antifibroproliferative activities. These properties of...

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Bibliographic Details
Main Authors: Paweł P. Antończak, Magdalena Jurzak, Katarzyna Adamczyk, Agnieszka Garncarczyk, Magdalena Hartman-Petrycka
Format: Article
Language:English
Published: Termedia Publishing House 2017-07-01
Series:Przegląd Dermatologiczny
Subjects:
tranilast
keloid fibroblasts
fibroblast activation protein α
FAP-α
Online Access:https://www.termedia.pl/The-effect-of-tranilast-on-fibroblast-activation-protein-FAP-expression-in-normal-and-keloid-fibroblasts-in-vitro-,56,30258,1,1.html

Internet

https://www.termedia.pl/The-effect-of-tranilast-on-fibroblast-activation-protein-FAP-expression-in-normal-and-keloid-fibroblasts-in-vitro-,56,30258,1,1.html

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