Optimizing the Pharmacological Properties of Discoidal Polymeric Nanoconstructs Against Triple-Negative Breast Cancer Cells

Optimizing the Pharmacological Properties of Discoidal Polymeric Nanoconstructs Against Triple-Negative Breast Cancer Cells

Fine-tuning loading and release of therapeutic and imaging agents associated with polymeric matrices is a fundamental step in the preclinical development of novel nanomedicines. Here, 1,000 × 400 nm Discoidal Polymeric Nanoconstructs (DPNs) were realized via a top-down, template-based fabrication ap...

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Bibliographic Details
Main Authors: Miguel Ferreira, Ilaria Francesca Rizzuti, Anna Lisa Palange, Maria Grazia Barbato, Valentina Di Francesco, Martina Di Francesco, Paolo Decuzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
polymeric particles
prodrugs
drug delivery
non-spherical shape
loading and release profiles
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00005/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00005/full

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