Changes in Drug Utilization After Publication of Clinical Trials and Drug-Related Scandals in Japan: An Interrupted Time Series Analysis, 2005–2017

Changes in Drug Utilization After Publication of Clinical Trials and Drug-Related Scandals in Japan: An Interrupted Time Series Analysis, 2005–2017

Background: Breaches of ethics undermine the practice of medicine. In Japan, two major scandals involving clinical research and drug marketing occurred after the publication of clinical trials. To study the effects of those scandals, we evaluated changes in the use of first-generation angiotensin II...

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Bibliographic Details
Main Authors: Shingo Fukuma, Tatsuyoshi Ikenoue, Yukari Yamada, Yoshiyuki Saito, Joseph Green, Takeo Nakayama, Shunichi Fukuhara
Format: Article
Language:English
Published: Japan Epidemiological Association 2021-07-01
Series:Journal of Epidemiology
Subjects:
clinical trial
drug utilization
research scandal
interrupted time series analysis
Online Access:https://www.jstage.jst.go.jp/article/jea/31/7/31_JE20200181/_pdf

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https://www.jstage.jst.go.jp/article/jea/31/7/31_JE20200181/_pdf

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