In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections.

BACKGROUND: Few effective drugs are available for soil-transmitted helminthiases and drug resistance is of concern. In the present work, we tested the efficacy of the veterinary drug monepantel, a potential drug development candidate compared to standard drugs in vitro and in parasite-rodent models...

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Bibliographic Details
Main Authors: Lucienne Tritten, Angelika Silbereisen, Jennifer Keiser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3246443?pdf=render