Safety and efficacy of ex vivo expanded CD34+ stem cells in murine and primate models

Safety and efficacy of ex vivo expanded CD34+ stem cells in murine and primate models

Abstract Background Hematopoietic stem cell (HSC) transplantation has been widely applied to the treatment of malignant blood diseases. However, limited number of functional HSCs hinders successful transplantation. The purpose of our current study is to develop a new and cost-efficient medium formul...

Full description

Bibliographic Details
Main Authors: Yu Zhang, Bin Shen, Xin Guan, Meng Qin, Zhihua Ren, Yupo Ma, Wei Dai, Xinxin Ding, Yongping Jiang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
Long-term HSC
Ex vivo expansion
Human cord blood
Transplantation
NOD/SCID mice
Nonhuman primates
Online Access:http://link.springer.com/article/10.1186/s13287-019-1275-0

Internet

http://link.springer.com/article/10.1186/s13287-019-1275-0

Similar Items