Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics

Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics

Superparamagnetic iron oxide nanoparticles (SPION) are employed as diagnostics and therapeutics following intravenous delivery for the treatment of iron deficiency anemia (IDA) in adult patients with chronic kidney failure. Neutrophils are the first defense against blood borne foreign insult and rec...

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Bibliographic Details
Main Authors: Gustavo Garcia, Min-Ho Kim, Vasilios Aris Morikis, Scott I. Simon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
neutrophil recruitment
nanoparticle
iron oxide
inflammation
neutrophil degranulation
mechanosignaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.571489/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.571489/full

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