Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3–Mcl-1 signaling

Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3–Mcl-1 signaling

Abstract Background Despite being one of the leading cancer types in the world, the diagnosis of oral cancer and its suitable therapeutic options remain limited. This study aims to investigate the single and chemosensitizing effects of TW-37, a BH3 mimetic in oral cancer, on human oral cancer cell l...

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Bibliographic Details
Main Authors: In-Hyoung Yang, Seung-Hyun Hong, Minjung Jung, Chi-Hyun Ahn, Hye-Jung Yoon, Seong Doo Hong, Sung-Dae Cho, Ji-Ae Shin
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cancer Cell International
Subjects:
TW-37
Cryptotanshinone
Chemosensitivity
STAT3
Mcl-1
Oral cancer
Online Access:http://link.springer.com/article/10.1186/s12935-020-01495-2

Internet

http://link.springer.com/article/10.1186/s12935-020-01495-2

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