Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes

In glioblastoma multiforme (GBM), brain-tumor-initiating cells (BTICs) with cancer stem cell characteristics have been identified and proposed as primordial cells responsible for disease initiation, recurrence, and therapeutic resistance. However, the extent to which individual, patient-derived BTIC...

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Bibliographic Details
Main Authors: Carlo Cusulin, Charles Chesnelong, Pinaki Bose, Misha Bilenky, Karen Kopciuk, Jennifer A. Chan, J. Gregory Cairncross, Steven J. Jones, Marco A. Marra, H. Artee Luchman, Samuel Weiss
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001538