The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.

Schistosomiasis affects millions of people in developing countries and is responsible for more than 200,000 deaths annually. Because of toxicity and limited spectrum of activity of alternatives, there is effectively only one drug, praziquantel, available for its treatment. Recent data suggest that d...

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Bibliographic Details
Main Authors: Peter D Ziniel, Bhargava Karumudi, Andrew H Barnard, Ethan M S Fisher, Gregory R J Thatcher, Larissa M Podust, David L Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4694641?pdf=render