Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification

Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification

DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.

Bibliographic Details
Main Authors: Sefi Vernick, Scott M. Trocchia, Steven B. Warren, Erik F. Young, Delphine Bouilly, Ruben L. Gonzalez, Colin Nuckolls, Kenneth L. Shepard
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15450

Internet

https://doi.org/10.1038/ncomms15450

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