A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

Long noncoding RNAs (lncRNAs) regulate key steps of cell division. Here, the authors perform a comprehensive RNAi imaging screen targeting more than 2,000 human lncRNAs, and suggest a role of chromatin-associated linc00899 in regulation of cell division by suppressing the transcription of microtubul...

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Bibliographic Details
Main Authors: Lovorka Stojic, Aaron T. L. Lun, Patrice Mascalchi, Christina Ernst, Aisling M. Redmond, Jasmin Mangei, Alexis R. Barr, Vicky Bousgouni, Chris Bakal, John C. Marioni, Duncan T. Odom, Fanni Gergely
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14978-7

Internet

https://doi.org/10.1038/s41467-020-14978-7

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