Bacterial Carriers for Glioblastoma Therapy

Bacterial Carriers for Glioblastoma Therapy

Treatment of aggressive glioblastoma brain tumors is challenging, largely due to diffusion barriers preventing efficient drug dosing to tumors. To overcome these barriers, bacterial carriers that are actively motile and programmed to migrate and localize to tumor zones were designed. These carriers...

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Bibliographic Details
Main Authors: Nalini Mehta, Johnathan G. Lyon, Ketki Patil, Nassir Mokarram, Christine Kim, Ravi V. Bellamkonda
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
brain cancer
bacteria
drug delivery
tumor targeting
glioblastoma
Salmonella typhimurium
p53
Azurin
VNP 20009
RNU rats
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770516300572

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http://www.sciencedirect.com/science/article/pii/S2372770516300572

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