Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line

A key morphological feature of inflammatory bowel disease (IBD) is the loss of the barrier function of intestinal epithelial cells. The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induce...

Full description

Bibliographic Details
Main Authors: Mohamad Toutounji, Dalanda Wanes, Mohammad El-Harakeh, Marwan El-Sabban, Sandra Rizk, Hassan Y. Naim
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
endoplasmic reticulum stress
anti- and pro-inflammatory cytokines
inflammatory bowel disease
cholesterol
brush border membranes
sucrase-isomaltase
Online Access:https://www.mdpi.com/1422-0067/21/8/2726

Internet

https://www.mdpi.com/1422-0067/21/8/2726

Similar Items