Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3′ untranslated region of TRIT1

Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3′ untranslated region of TRIT1

Noncoding regions of the genome play an important role in tumorigenesis of cancer. Using expression cloning, we have identified a cytotoxic T lymphocyte (CTL)–defined antigen that recognizes a protein sequence derived from an open reading frame transcribed from the reverse strand in the 3′ untransla...

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Bibliographic Details
Main Authors: Rolf K Swoboda, Rajasekharan Somasundaram, Laura Caputo-Gross, Francesco M Marincola, Paul Robbins, Meenhard Herlyn, Dorothee Herlyn
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770516300031

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http://www.sciencedirect.com/science/article/pii/S2372770516300031

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