Non-invasive imaging using reporter genes altering cellular water permeability

Magnetic resonance imaging combined with molecular reporters can visualise cellular functions in intact organisms. Here Mukherjeeet al. present a cellular imaging approach based on intracellular changes in water diffusion using human aquaporin 1 gene as a genetically encoded reporter for MRI.

Bibliographic Details
Main Authors: Arnab Mukherjee, Di Wu, Hunter C. Davis, Mikhail G. Shapiro
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13891