Reduction in number to treat versus number needed to treat

Abstract Background We propose a new measure of treatment effect based on the expected reduction in the number of patients to treat (RNT) which is defined as the difference of the reciprocals of clinical measures of interest between two arms. Compared with the conventional number needed to treat (NN...

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Bibliographic Details
Main Authors: Chenyang Zhang, Guosheng Yin
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-021-01246-5