Glucagon-like peptide-1 analogue, liraglutide, delays onset and reduces severity of experimental autoimmune encephalitis in Lewis rats

Glucagon-like peptide-1 analogue, liraglutide, delays onset and reduces severity of experimental autoimmune encephalitis in Lewis rats

AbstractIntroduction: Recent findings indicate that metabolic disturbances are involved in multiple sclerosis (MS) pathology and influence the susceptibility to treatment, directing attention towards anti-diabetic drugs such as metformin and pioglitazone. Liraglutide, a drug of the glucagon-like pep...

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Bibliographic Details
Main Authors: Brian DellaValle, Gitte Brix, Birgitte Brock, Michael Gejl, Anne Landau, Arne Møller, Jørgen Rungby, Agnete Larsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Multiple Sclerosis
EAE
APP
MS
GLP-1
liraglutide
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00433/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00433/full

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