Inhibition of IRE1 signaling affects the expression of genes encoded glucocorticoid receptor and some related factors and their hypoxic regulation in U87 glioma cells

Objective. The aim of the present investigation was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of genes encoding glucocorticoid receptor...

Full description

Bibliographic Details
Main Authors: Minchenko D.O., Riabovol O.O., Tsymbal D.O., Ratushna O.O., Minchenko O.H.
Format: Article
Language:English
Published: Sciendo 2016-07-01
Series:Endocrine Regulations
Subjects:
nnt
Online Access:https://doi.org/10.1515/enr-2016-0014