The KDM4B–CCAR1–MED1 axis is a critical regulator of osteoclast differentiation and bone homeostasis

Abstract Bone undergoes a constant and continuous remodeling process that is tightly regulated by the coordinated and sequential actions of bone-resorbing osteoclasts and bone-forming osteoblasts. Recent studies have shown that histone demethylases are implicated in osteoblastogenesis; however, litt...

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Bibliographic Details
Main Authors: Sun-Ju Yi, You-Jee Jang, Hye-Jung Kim, Kyubin Lee, Hyerim Lee, Yeojin Kim, Junil Kim, Seon Young Hwang, Jin Sook Song, Hitoshi Okada, Jae-Il Park, Kyuho Kang, Kyunghwan Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00145-1