A distinct mechanism of vascular lumen formation in Xenopus requires EGFL7.

During vertebrate blood vessel development, lumen formation is the critical process by which cords of endothelial cells transition into functional tubular vessels. Here, we use Xenopus embryos to explore the cellular and molecular mechanisms underlying lumen formation of the dorsal aorta and the pos...

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Bibliographic Details
Main Authors: Marta S Charpentier, Panna Tandon, Claire E Trincot, Elitza K Koutleva, Frank L Conlon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0116086