Expression of FOXP3, CD14, and ARG1 in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival

Expression of FOXP3, CD14, and ARG1 in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival

The prognosis of children with metastatic neuroblastoma (NB) > 18 months at diagnosis is dismal. Since the immune status of the tumor microenvironment could play a role in the history of disease, we evaluated the expression of CD45, CD14, ARG1, CD163, CD4, FOXP3, Perforin-1 (PRF1), Granzyme B (GR...

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Bibliographic Details
Main Authors: Sara Stigliani, Michela Croce, Fabio Morandi, Paola Scaruffi, Valentina Rigo, Barbara Carlini, Carla Manzitti, Anna Rita Gigliotti, Gian Paolo Tonini, Vito Pistoia, Silvano Ferrini, Maria Valeria Corrias
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/347867

Internet

http://dx.doi.org/10.1155/2015/347867

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