Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade

Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade

The anti-inflammatory agents glucocorticoids (GC) are the only available treatment for Duchenne muscular dystrophy (DMD). However, long-term GC treatment causes muscle atrophy and wasting. Thus, targeting specific mediator of inflammatory response may be more specific, more efficacious, and with few...

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Bibliographic Details
Main Authors: Laura Pelosi, Maria Grazia Berardinelli, Loredana De Pasquale, Carmine Nicoletti, Adele D'Amico, Francesco Carvello, Gian Marco Moneta, Angela Catizone, Enrico Bertini, Fabrizio De Benedetti, Antonio Musarò
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:EBioMedicine
Subjects:
IL6
Muscular dystrophy
Inflammation
Necrosis
Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000626

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http://www.sciencedirect.com/science/article/pii/S2352396415000626

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