Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress

Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress

The present study aimed to analyze novel mechanisms underlying Nrf2-mediated anti-apoptosis in periodontal ligament stem cells (PDLSCs) in the periodontitis oxidative microenvironment. We created an oxidative stress model with H2O2-treated PDLSCs. We used real-time PCR, Western blotting, TUNEL stain...

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Bibliographic Details
Main Authors: Yanli Liu, Hongxu Yang, Yi Wen, Bingyi Li, Yinhua Zhao, Jing Xing, Min Zhang, Yongjin Chen
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:International Journal of Molecular Sciences
Subjects:
periodontitis
periodontal ligament stem cells
nuclear factor-erythroid 2-related factor 2
oxidative stress
apoptosis
Online Access:http://www.mdpi.com/1422-0067/18/5/1076

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http://www.mdpi.com/1422-0067/18/5/1076

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