N-staging in large cell neuroendocrine carcinoma of the lung: diagnostic value of [18F]FDG PET/CT compared to the histopathology reference standard

N-staging in large cell neuroendocrine carcinoma of the lung: diagnostic value of [18F]FDG PET/CT compared to the histopathology reference standard

Abstract Background Large cell neuroendocrine carcinoma of the lung (LCNEC) is a rare entity occurring in less than 4% of all lung cancers. Due to its low differentiation and high glucose transporter 1 (GLUT1) expression, LCNEC demonstrates an increased glucose turnover. Thus, PET/CT with 2-[18F]-fl...

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Bibliographic Details
Main Authors: Hubertus Hautzel, Yazan Alnajdawi, Wolfgang P. Fendler, Christoph Rischpler, Kaid Darwiche, Wilfried E. Eberhardt, Lale Umutlu, Dirk Theegarten, Martin Stuschke, Martin Schuler, Clemens Aigner, Ken Herrmann, Till Plönes
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:EJNMMI Research
Subjects:
[18F]FDG
PET/CT
Large cell neuroendocrine carcinoma
Lung
Nodal staging
Online Access:https://doi.org/10.1186/s13550-021-00811-9

Internet

https://doi.org/10.1186/s13550-021-00811-9

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