Ribosome stalling caused by the Argonaute-microRNA-SGS3 complex regulates the production of secondary siRNAs in plants

Summary: The path of ribosomes on mRNAs can be impeded by various obstacles. One such example is halting of ribosome movement by microRNAs, but the exact mechanism and physiological role remain unclear. Here, we find that ribosome stalling caused by the Argonaute-microRNA-SGS3 complex regulates prod...

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Bibliographic Details
Main Authors: Hiro-oki Iwakawa, Andy Y.W. Lam, Akira Mine, Tomoya Fujita, Kaori Kiyokawa, Manabu Yoshikawa, Atsushi Takeda, Shintaro Iwasaki, Yukihide Tomari
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006768